Abnormal night melatonin level in a patient with well-controlled epilepsy without sleep disturbances – could it be associated with levetiracetam therapy: A case report

نویسندگان

چکیده

We present a case report of 23-year old male with newly diagnosed epilepsy manifested generalized tonic seizures. Levetiracetam (LEV) was started and the patient seizure free. The demonstrated intermediate chronotype determined by Morningness-Eveningness Questionnaire (MEQ). There no epileptiform activity on electroencephalography (EEG) polysomnography (PSG), sleep architecture disturbances (PSG) or daytime sleepiness (Epworth score, Multiple latency test) at onset after 3 months LEV therapy. melatonin serum levels treatment were 22.00 pg/ml a.m. 23.60 8 - there normal night peak concentration. This abnormality may be associated later concentration, levetiracetam being possible explanation. consider presented clinical special interest because combination absence parameters non-extremely chronotype. suggest that such patients could benefit from add-on therapy melatonin.

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ژورنال

عنوان ژورنال: World Journal Of Advanced Research and Reviews

سال: 2021

ISSN: ['2581-9615']

DOI: https://doi.org/10.30574/wjarr.2021.10.3.0239